Founding of AVIGI
At AVIGI Therapeutics, we don’t just think outside the box—we dissolve it, analyze it, and reassemble it into something extraordinary. Our journey began with an unlikely hero: the disaccharide. These small sugar molecules may seem unassuming, but within their structure lies the blueprint for a groundbreaking heparanase inhibitor.
Why heparanase? This enzyme plays a key role in tissue remodeling, cancer metastasis, and inflammatory diseases, making it a prime target for therapeutic intervention. Inspired by nature’s own molecules, our team engineered a disaccharide-inspired inhibitor capable of selectively halting heparanase activity without disrupting healthy cellular processes.
This was innovation + biomimicry at its finest, with added scientific flair for problem-solving. By applying design principles to our understanding of molecular interactions and biology, we’ve turned a humble sugar into a precision therapeutic tool against some of the toughest diseases.
Follow our advancement by subscribing
Timeline
A snapshot of some of our public milestones
UNIIQ Boosts AVIGI
Our first commitment from the regional development fund of South-Holland, The Netherlands, funding our development efforts with a 350K EUR CLA.
Founding AVIGI Therapeutics
We incorporated the company under a new bold name: AVIGI Therapeutics B.V. Headquartered in Leiden, The Netherlands
Unlock_ Incubator
Joined Unlock_ in Leiden to get incubated.
Venture Challenge
We participated in the Venture Challenge Winter Cohort of 2023, back then with the name Triangle Therapeutics
Early startup story Lifesciencesatwork.nlERC and NWO PoC Funding
European Research Council and NWO awarded the project funding
Grant EU Website Cordis.europa.euDiscovery of our lead candidate
Composition of matter patent application submitted. Key innovations published.
Structural Mechanism rcsb.org